![]() ![]() ![]() PDGF-BB also stimulated MAPK/ERK phosphorylation, which was inhibited by AG1296 or naloxone, indicative of a cross-talk between PDGFR-β and OPs. Morphine-induced phosphorylation of MAPK/ERK was abrogated by naloxone and by AG1296, a pharmacological inhibitor of PDGFR, suggesting that morphine stimulates mitogenic signalling via OPs and PDGFR-β (Fig. Mesangial cells stimulated with morphine in vitro showed a time-dependent increase in the phosphorylation of PDGFR-β and MAPK/ERK (Fig. Special Issue on Memory and Awareness in Anesthesia (PDF).Special Issue on Mass Casualty Medicine and Anaesthesia: Science and Clinical Practice (JPG).Special Issue on Thoracic Anaesthesia and Respiratory Physiology (PDF).Hong Kong College of Anaesthesiologists.College of Anaesthesiologists of Ireland.Memory, Awareness and Anaesthesia 2022 Special Collection.COVID-19 and the Anaesthetist: A Special Series.
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